TWiV reviews results of a phase 3 trial of a self-amplifying mRNA COVID-19 vaccine, and the finding that baseline innate and T cell populations are correlates of protection against symptomatic influenza virus infection independent of serology.

Hosts: Dickson DespommierAlan Dove and Brianne Barker

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Links for this episode MicrobeTV Discord Server MicrobeTV store at Cafepress Michelson Prizes: Next Generation Grants Immunogenicity and safety of self-amplifying mRNA COVID-19 vaccine (Lancet Inf Dis) First self-amplifying mRNA vaccine approved in Japan (Science) Rise of the RNA machines (Trends Biochem) Innate and T cell populations correlates of protection against influenza (Nat Immunol) Timestamps by Jolene. Thanks! Weekly Picks

Dickson - Nitrogen-fixing organelle in a marine alga
Brianne – Mapping a lost branch of the Nile
Alan – Interactive version of the updated USDA gardening zone map on NPR.

Intro music is by Ronald Jenkees

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