American Journal of Psychiatry Audio
205 episodes - English - Latest episode: 2 days ago - ★★★★ - 69 ratingsEach episode of AJP Audio brings you an in-depth look at one of the articles featured in that month’s issue of The American Journal of Psychiatry, the official journal of the American Psychiatric Association. Wide-ranging interviews with article authors cover the background, rationale, main findings, and future implications of the research.
This podcast is subject to the Terms of Use at ww.psychiatry.org. The views and opinions expressed in this podcast are those of the individual speakers only and do not necessarily represent the views of the American Psychiatric Association, its officers, trustees, or members. The content of this podcast is provided for general informational purposes only and is not intended as, and shall not be understood or construed as, medical or any other type of professional advice nor does it represent any statement of the standard of care. We strongly recommend that any listener follow the advice of physicians directly involved in their care and contact their local emergency response number for any medical emergency. The information within this podcast is provided as-is and is not guaranteed to be correct, complete, or accurate.
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Episodes
June 2024: Long-Term Course of Remission and Recovery in Psychotic Disorders
June 01, 2024 04:00 - 29 minutes - 40.5 MBMs. Sara Tramazzo (Stony Brook University) joins AJP Audio to discuss the long-term outlook for patients with schizophrenia spectrum disorders and other psychotic disorders over the course of 25 years. Afterwards, Dr. Ned Kalin joins to discuss the rest of the June issue of AJP. 00:50 Tramazzo interview 01:55 Lower levels of recovery and remission than other long-term studies 03:01 Difficulties of following patients in long-term studies 04:35 Differences between r...
May 2024: Predictors of Substance Use Initiation by Early Adolescence
May 06, 2024 09:00 - 36 minutes - 50.6 MBDr. ReJoyce Green (Medical University of South Carolina, Charleston, SC) joins AJP Audio to discuss predictors of substance use initiation in a large cohort of early adolescents. Afterwards, AJP Editor-in-Chief Dr. Ned Kalin speaks with AJP Deputy Editor Dr. Kathleen Brady about the May issue of AJP, a special issue guest edited by Dr. Brady focusing on latest developments in the understanding and treatment of substance use disorders. Transcript 00:48 Green interview 03:04 Why...
April 2024: Neural Responses to Intranasal Oxytocin in Youths With Severe Irritability
April 01, 2024 09:00 - 27 minutes - 38 MBDr. Soonjo Hwang (University of Nebraska Medical Center) joins AJP Audio to discuss the response to intranasally-administered oxytocin in youths with severe irritability. 00:56 Hwang interview 02:09 Effects of oxytocin 05:45 Intranasal oxytocin 07:04 Potential adverse effects of oxytocin 08:08 Imaging 08:58 Preliminary investigations and clinical implications 09:51 Limitations 10:14 Further research 11:00 Kalin interview 11:33 Hwang ...
March 2024: Intergenerational Effects of the Fast Track Intervention on Next-Generation Child Outcomes: A Preregistered Randomized Clinical Trial
March 01, 2024 10:00 - 27 minutes - 38.3 MBDr. Drew Rothenberg (Duke University, Durham, NC) joins AJP Audio to discuss the long term, intergenerational impacts of the Fast Track program, and whether the mental health intervention lead to lasting improvements in mental health, including in the participants own children. 00:49 Rothenberg interview 04:36 A null result? 07:13 At risk children from high risk neighborhoods 08:00 Limitations 09:17 Demand for childhood mental health services and clinica...
February 2024: Trends in Prevalence of Cannabis Use Disorder Among U.S. Veterans With and Without Psychiatric Disorders Between 2005 and 2019
February 01, 2024 10:00 - 21 minutes - 30.3 MBDr. Ofir Livne (Columbia University, New York) joins AJP Audio to discuss recent trends in the prevalence of cannabis use disorder in US veterans with and without psychiatric disorder diagnosis. Dr. Ned Kalin joins afterwards to discuss how the rest of the February issue of AJP touches on cannabis use disorder and other substance use disorders. 00:31 Livne interview 03:16 Changes in the legal landscape surrounding cannabis use 05:17 The complex association between cannab...
January 2024: Predicting Acute Changes in Suicidal Ideation and Planning: A Longitudinal Study of Symptom Mediators and the Role of the Menstrual Cycle in Female Psychiatric Outpatients With Suicidality
January 01, 2024 10:00 - 35 minutes - 48.8 MBDr. Jaclyn Ross, Ms. Jordan Barone, and Dr. Tory Eisenlohr-Moul (University of Illinois at Chicago) join AJP Audio to discuss the impact of the menstrual cycle on suicide ideation and planning in psychiatric patients with suicidality. Afterwards, American Journal of Psychiatry Editor-in-Chief Dr. Ned Kalin brings us up to date on the rest of the January issue of AJP. Transcript Be sure to let your colleagues know about the podcast, and please rate and review it on Apple Podcasts, ...
December 2023: Racial and Ethnic Disparities in COVID-19-Related Stressor Exposure and Adverse Mental Health Outcomes Among Health Care Workers
December 01, 2023 10:00 - 28 minutes - 38.6 MBDr. Aaron Samuel Breslow (Montefiore Medical Center and Albert Einstein College of Medicine) joins AJP Audio to discuss the racial and ethnic disparities in the impact of COVID-19 and pandemic related stressors and adverse mental health outcomes on health care workers in the Bronx, New York. Following we’ll once again check in with American Journal of Psychiatry Editor-in-Chief Dr. Ned Kalin on the rest of the December issue of AJP. Breslow interview [00:56] Why look at the Bronx in p...
November 2023: Inequalities in the Incidence of Psychotic Disorders Among Racial and Ethnic Groups
November 01, 2023 09:00 - 19 minutes - 27.4 MBDr. Winston Chung (Kaiser Permanente Northern California) joins AJP Audio to discuss inequalities in the diagnosis of psychotic disorders between racial and ethnic groups in a large cohort. Afterwards, we’ll once again be joined by American Journal of Psychiatry Editor-in-Chief, Dr. Ned Kalin, to discuss the rest of the November issue of AJP, which focuses on different aspects of psychotic disorder. Chung interview [00:30] Structural racism and missing socioeconomic strata [02:58] E...
October 2023: Networks of Neurodevelopmental Traits, Socioenvironmental Factors, Emotional Dysregulation in Childhood, and Depressive Symptoms Across Development in Two U.K. Cohorts
October 01, 2023 09:00 - 28 minutes - 39.8 MBDr. Luis Farhat and Dr. Guilherme V. Polanczyk (University of São Paulo, Brazil) join AJP Audio to discuss the impact of socioenviromental factors, emotional dysregulation, and other factors impact neurodevelopment in children. Afterwards, we’ll once again be joined by American Journal of Psychiatry Editor-in-Chief, Dr. Ned Kalin, to discuss the rest of the September issue of AJP and what brings it together. Farhat and Polanczyk interview [00:54] Comorbidities and associations [03:22] ...
September 2023: Disparities in Suicide-Related Behaviors Across Sexual Orientations by Gender: A Retrospective Cohort Study Using Linked Health Administrative Data
September 01, 2023 09:00 - 24 minutes - 33.4 MBDr. Antony Chum (York University, Toronto) joins AJP Audio to discuss disparities in suicide-related behaviors between sexual orientations by gender in a large cohort from the province of Ontario. Afterwards, we’ll once again be joined by American Journal of Psychiatry Editor-in-Chief, Dr. Ned Kalin, to discuss the rest of the September issue of AJP and what brings it together. Transcript Chum interview [00:34] Results [02:14] Using a large data set [03:21] Correcting the limita...
August 2023: A Comprehensive Multilevel Analysis of the Bucharest Early Intervention Project: Causal Effects on Recovery From Early Severe Deprivation
August 01, 2023 08:39 - 32 minutes - 45.1 MBDr. Lucy S. King (Tulane University School of Medicine, New Orleans) and Dr. Kathryn L. Humphreys (Vanderbilt University, Nashville) join AJP Audio to discuss the long term impacts of a pioneering randomized controlled trial that looked at the impacts of institutional care versus home foster care in children, the Bucharest Early Intervention Project. They also discuss the impacts of deprivation on children’s development and mental health, and the thorny ethics of research involving childre...
July 2023: Differences in Social Determinants of Health Underlie Racial/Ethnic Disparities in Psychological Health and Well-Being: Study of 11,143 Older Adults
July 01, 2023 12:00 - 22 minutes - 30.8 MBDr. Dylan J. Jester (VA Palo Alto Medical Center in Palo Alto, California) joins AJP Audio to discuss the differential impact of selected social determinants of health on the mental health outcomes of older Black, White, and Latinx adults in the United States. Afterwards, AJP Editor-in-Chief Dr. Ned Kalin discusses how issues of substance use disorder draw together the rest of the July issue. Transcript Jester interview [00:48] Which social determinants of health did you focus on? [...
June 2023: Opioid Prescribing and Suicide Risk in the United States
June 01, 2023 09:00 - 16 minutes - 22.5 MBDr. Mark Olfson (Columbia University) discusses the links between opioid prescribing and suicide risk in the United States. Afterwards, AJP Editor-in-Chief Dr. Ned Kalin discusses how issues of substance use disorder draw together the rest of the June issue. Transcript Olfson interview [00:46] Geographic commuting areas [01:06] Opioid prescription measures [02:10] Rates of opioid prescription and suicide [03:27] Youngest age cohorts as outliers [04:19] Regional variatio...
May 2023: Attention Bias Modification Treatment Versus a Selective Serotonin Reuptake Inhibitor Or Waiting List Control for Social Anxiety Disorder
May 01, 2023 13:52 - 20 minutes - 27.7 MBMs. Gal Arad (Tel Aviv University, Tel Aviv, Israel) discusses a non-pharmacological intervention for the treatment of social anxiety disorder in comparison with standard care. Afterwards, we’ll be joined once again by AJP Editor-in-Chief Dr. Ned Kalin to discuss the rest of the May issue. Transcript Arad interview [00:18] What were your results? [02:11] Reduction in dwell time on threatening faces [03:36] Limitations [04:09] Immediate clinical implications [05:27] Furthe...
April 2023: Translational Neuroscience Approaches to Understanding Autism
April 03, 2023 14:26 - 29 minutes - 41.2 MBDr. David G. Amaral (University of California, Davis) is an author of a review paper in the April issue of AJP looking at the use of animal models and other forms of translational neuroscience in the investigation of autism spectrum disorder. He joins us on AJP Audio to discuss it. Afterwards, we’ll be joined once again by AJP Editor-in-Chief Dr. Ned Kalin to discuss the rest of the April issue. Transcript Amaral interview [00:56] Advantages and disadvantages of animal mod...
March 2023: Adjunctive Cariprazine for the Treatment of Patients With Major Depressive Disorder
March 01, 2023 14:27 - 24 minutes - 33.7 MBDr. Gary S. Sachs (Harvard Medical School) joins us for the for the March episode of AJP Audio, discussing the results from a phase 3 study looking at the use of atypical antipsychotic cariprazine as an adjunctive treatment for major depression in conjunction with antidepressants. Afterwards, we’ll be joined once again by AJP Editor-in-Chief Dr. Ned Kalin to discuss the rest of the March issue. Transcript Sachs interview [00:47] Why is treating major depressive disorder in patient...
February 2023: Adversity, Toxic Stress, and Racial Disparities in Children, and Evaluating the Evidence for Brain-Based Biotypes
February 01, 2023 15:19 - 39 minutes - 54.6 MBThis episode of AJP Audio features two articles from the February issue of AJP. First up, we have Nathaniel G. Harnett, Ph.D. (Harvard Medical School), discussing the impact of adversity and stress on racial disparities in childhood brain development among Black and White American children. Following that, Ziv Ben-Zion, Ph.D. (Yale University), discusses a non-exact replication study of a study published in AJP by Stevens et al. (previously featured on AJP Audio) looking at brain-based bi...
January 2023: Resting-State Connectivity and Response to Psychotherapy Treatment in Adolescents and Adults With OCD: A Randomized Clinical Trial
January 03, 2023 16:04 - 30 minutes - 42.4 MBDr. Stefanie Russman Block (University of Michigan, Ann Arbor) discusses a trial looking at whether connectivity patterns in the brain can be used to predict treatment response in patients with obsessive-compulsive disorder. Afterwards, AJP Editor-in-Chief Dr. Ned Kalin discusses childhood and neurodeveloment-related psychiatric disorders explored in the January issue. Russman Block interview [00:51] Exposure and response prevention versus stress management therapy [05:46] Investigatin...
December 2022: A Novel, Brief, Fully Automated Intervention to Extend the Antidepressant Effect of a Single Ketamine Infusion: A Randomized Clinical Trial
December 01, 2022 16:53 - 29 minutes - 40.6 MBDr. Rebecca Price (University of Pittsburgh) discusses a novel, computer-based intervention designed to extend the antidepressant effects of a single dose of ketamine. Afterwards, AJP Editor-in-Chief Dr. Ned Kalin discusses the rest of the December issue and what draws it together. Price interview [00:40] What does the computer-based intervention consist of? [03:55] Comparator arms [05:25] Are there immediate clinical implications? [08:04] Limitations [10:19] Further research [12:...
November 2022: Leveraging Large-Scale Genetics of PTSD and Cardiovascular Disease to Demonstrate Robust Shared Risk and Improve Risk Prediction Accuracy
November 01, 2022 18:49 - 26 minutes - 36 MBDr. Antonia Seligowski (McLean Hospital and Harvard Medical School) discusses how significant genetic correlations were identified between PTSD and cardiovascular disease as well as support for a causal link from PTSD to hypertension and coronary artery disease. Afterwards, AJP Editor-in-Chief Dr. Ned Kalin discusses the rest of the November issue and what draws it together. Seligowski interview [00:50] Genome-wide association studies [02:24] The Mass General Brigham Biobank [03:05] ...
October 2022: Neural Signatures of Pain Modulation in Short-Term and Long-Term Mindfulness Training
October 03, 2022 17:33 - 25 minutes - 35.4 MBDr. Richard Davidson (University of Wisconsin-Madison) discusses the effects of mindfulness training on the neural mechanisms of pain and what it means for the future of pain management. Afterwards, AJP Editor-in-Chief Dr. Ned Kalin discusses what draws together that paper and the rest of the October issue. Davidson interview [00:37] How do you go about investigating pain? [05:41] Lack of apparent difference in neural response among long-term meditators [06:45] What does this mean for...
September 2022: Persistent Dissociation and Its Neural Correlates in Predicting Outcomes After Trauma Exposure
September 01, 2022 13:17 - 36 minutes - 50.1 MBDr. Lauren A. M. Lebois (Dissociative Disorders and Trauma Research Program, McLean Hospital, Harvard Medical School) discusses persistent dissociation following trauma exposure and whether it can be predictive of later psychiatric outcomes in at risk populations. Afterwards, AJP Editor-in-Chief Dr. Ned Kalin discusses the rest of the September issue and what draws it together. Lebois interview [00:52] A prototypical adult dissociation case [01:51] Dissociation as a rollercoaster [05:48...
August 2022: Subcortical Brain Development in Autism and Fragile X Syndrome
July 29, 2022 15:55 - 27 minutes - 38.1 MBDr. Mark D. Shen (University of North Carolina, Chapel Hill) discusses the trajectory of brain development in infants at risk for autism spectrum disorder (ASD) and fragile X syndrome. Longitudinal imaging was captured from 6 to 24 months to see how brain development differed between groups, and the development of the amygdala in infants at risk for ASD prior to onset of social deficits and clinical diagnosis. Shen interview [01:03] Why look at patients with potential ASD diagnosis in co...
July 2022: Digital Intervention for Cognitive Deficits in Major Depression
June 30, 2022 13:33 - 27 minutes - 38.4 MBDr. Richard S.E. Keefe (Duke University Medical Center, Durham, North Carolina) discusses an article looking at an intervention for major depressive disorder that takes the form of a videogame. Afterwards, AJP Editor-in-Chief Dr. Ned Kalin discusses the July issue’s theme. Keefe interview: [01:00] What were your results? [03:13] What do videogames offer as a depression intervention? [03:43] Differences between the intervention and the control intervention [05:05] What was the impact...
June 2022: Structural Racism and Mental Health Disparities
May 23, 2022 14:47 - 25 minutes - 35.4 MBAJP Editor-in-Chief Dr. Ned Kalin discusses the June issue with guest editor Dr. Crystal Barksdale (National Institute on Minority Health and Health Disparities). The issue focuses on mental health disparities, the pervasive negative consequences of structural racism, and the importance of community-wide and systemic interventions. Barksdale interview [00:30] How do mental health disparities differ for minoritized groups? [04:10] Structural and institutional racism as a factor in mental...
May 2022: The Emergence of Psychiatry: 1650–1850
May 01, 2022 12:00 - 35 minutes - 49.4 MBDr. Kenneth Kendler (Virginia Institute for Psychiatric and Behavioral Genetics at Virginia Commonwealth University, Roanoke, VA) discusses the history and emergence of psychiatry as a discipline, and how the conception of mind, body, and soul evolved. Afterwards, Journal Editor-in-Chief Dr. Ned Kalin discusses the May issue of AJP, and the past, present, and future of psychiatry. Kendler interview [00:45] Why is it important to look at the history of psychiatry? [10:28] The emergence o...
April 2022: Effects of County-Level Opioid Dispensing Rates on Individual-Level Patterns of Prescription Opioid and Heroin Consumption: Evidence From National U.S. Data
April 01, 2022 15:15 - 25 minutes - 34.7 MBDr. Brian Kelly (Purdue University, West Lafayette, Indiana) discusses a study that found recent efforts to curb opioid prescriptions appear to have had an effect on reducing prescription opioid misuse and dependence, with no evidence that shifts in local-level opioid dispensing affected odds of heroin use, frequency of heroin use, or heroin dependence. Afterwards, Journal Editor-in-Chief Dr. Ned Kalin discusses what pulls the March issue of AJP together. Kelly interview [00:30] Why coun...
March 2022: Genetics and Brain Transcriptomics of Completed Suicide
March 03, 2022 14:27 - 30 minutes - 42.4 MBDr. Giovanna Punzi and Dr. Daniel Weinberger (Lieber Institute for Brain Development, Baltimore, Maryland) discuss findings from their new paper, “Genetics and Brain Transcriptomics of Completed Suicide,” which looks at differences in the brains of those who die by violent versus less violent means of suicide. Afterwards, Journal Editor-in-Chief Dr. Ned Kalin discusses what pulls the March issue of AJP together. Punzi and Weinberger interview [00:43] What made the two categories distinct...
February 2022: Variable Patterns of Remission From ADHD in the Multimodal Treatment Study of ADHD
February 01, 2022 05:00 - 30 minutes - 42.3 MBDr. Margaret Sibley (University of Washington, Seattle, WA) joins the podcast this month to discuss an article from the February issue of the Journal looking at patterns of remission in attention deficit hyperactivity disorder in children. Dr. Ned Kalin, Editor-in-Chief of AJP will join us afterwards to discuss the rest of the February issue of the Journal. Sibley interview [00:51] What does “full remission” from ADHD mean? [01:54] Variable patterns of remission in children with ADHD ...
January 2022: Cannabis Use and the Endocannabinoid System
January 04, 2022 20:11 - 30 minutes - 41.6 MBIn this month’s AJP Audio, Dr Margert Haney (Director of the Cannabis Research Laboratory at Columbia Psychiatry) discusses her new review from the January issue of the American Journal of Psychiatry, “Cannabis Use and the Endocannabinoid System: A Clinical Perspective,” and the questions around the legal status of cannabis research. Afterward, Dr. Ned Kalin, Editor-in-Chief of the Journal discusses the January 2022 issue of AJP. Haney interview: How does cannabis interact with our brains?...
December 2021: Association of ECT With Risks of All-Cause Mortality and Suicide in Older Medicare Patients
December 01, 2021 14:02 - 25 minutes - 23.4 MBIn this month’s AJP Audio, Dr. Samuel Wilkinson (Yale University, Associate Director of the Yale Depression Research Program) discusses a study looking at the association of electro-convulsive therapy or ECT on all-cause mortality and suicide in Medicare patients with mood and bipolar disorders. Following that, Dr. Ned Kalin, Editor-in-Chief of the Journal discusses the December issue of AJP. Wilkinson interview: Effects of ECT on older patients with mood disorders [00:50] A brief histor...
November 2021: Using Neuroimaging to Classify Victims of Trauma
November 01, 2021 14:59 - 25 minutes - 23.5 MBDr. Jennifer Stevens (Assistant Professor of Psychiatry and Behavioral Sciences, Emory University) discusses a technique to classify trauma victims into discrete biotypes in the immediate aftermath of trauma, with the hope of providing insight into the groups that could guide treatment, and American Journal of Psychiatry Editor-in-Chief Dr. Ned Kalin puts the November, 2021 issue of AJP into context. Stevens interview [00:44] Using brain imaging data to understand how people respond t...
May 2021: Quality of Depression Care for Patients With Comorbid Substance Use Disorder
May 06, 2021 12:48 - 25 minutes - 25.2 MBExecutive Editor Michael Roy speaks with Lara N. Coughlin, Ph.D., and Lewei Allison Lin, M.D., M.S., about their article on the provision of guideline-concordant depression treatment to patients with and without substance use disorders. Dr. Lara Coughlin is an assistant professor in the Department of Psychiatry and an adjunct assistant professor of psychology at the University of Michigan. She is also a licensed clinical psychologist. Her research aims to find new ways to use behavioral ec...
April 2021: Reducing Adolescent Psychopathology in Socioeconomically Disadvantaged Children
April 01, 2021 11:30 - 30 minutes - 30.5 MBExecutive Editor Michael Roy speaks with Karen L. Bierman, Ph.D., about her article on reducing adolescent psychopathology in socioeconomically disadvantaged children with a preschool intervention. Dr. Karen Bierman is the Evan Pugh University Professor, Professor of Psychology, Professor of Human Development and Family Studies, and Director of the Child Study Center at Penn State University. Her research looks at the design and evaluation of programs for social and emotional learning with...
March 2021: Psychiatry Diversity Leadership in Academic Medicine
March 01, 2021 12:30 - 51 minutes - 50.2 MBExecutive Editor Michael Roy speaks with Ayana Jordan, M.D., Ph.D., and Christina Mangurian, M.D., M.A.S., about their article on psychiatry diversity leadership in academic medicine. Dr. Ayana Jordan is an associate program director of the adult psychiatry training program and an assistant professor of psychiatry at the Yale University School of Medicine. She is a member of the APA Board of Trustees, and she serves on the Early-Career Psychiatrist Advisory Committee for the journal Psychi...
February 2021: Maternal Psychological Resilience and Newborn Telomere Length
February 01, 2021 12:30 - 29 minutes - 28.5 MBExecutive Editor Michael Roy speaks with Glenn Verner, M.P.H., and Sonja Entringer, Ph.D., about their article on the relationship between maternal psychological resilience during pregnancy and newborn telomere length. Ms. Glenn Verner is a doctoral candidate in medical psychology at Charité University Medicine in Berlin. She is interested in studying the biological mechanisms that underpin maternal and fetal health. Dr. Sonja Entringer is a professor of medical psychology at Charité Uni...
January 2021: Brain Activation and Symptom Reduction in OCD Following CBT
January 01, 2021 12:30 - 29 minutes - 28 MBExecutive Editor Michael Roy speaks with Luke J. Norman, Ph.D., and Kate D. Fitzgerald, M.D., about their article examining whether brain activity is associated with treatment response to cognitive-behavioral therapy (CBT) in adolescents and adults with obsessive-compulsive disorder (OCD), and whether any associations are treatment specific relative to an active control psychotherapy (stress management therapy; SMT). Dr. Luke Norman was recently a neuroscience postdoctoral fellow at the Un...
December 2020: Year in Review
December 01, 2020 12:30 - 41 minutes - 39.2 MBExecutive Editor Michael Roy speaks with American Journal of Psychiatry Editor-in-Chief Ned H. Kalin, M.D., and Deputy Editor Carolyn Rodriguez, M.D., Ph.D., about the Journal’s response to COVID-19; strategies to combat racism, social injustice, and health care inequities; research highlights from the past year; and what lies ahead in 2021. Dr. Kalin is the Hedberg Professor and Chair of the Department of Psychiatry at the University of Wisconsin School of Medicine and Public Health, wher...
November 2020: Brain Responses During Treatment for Alcohol Use Disorder
November 01, 2020 12:30 - 32 minutes - 31.4 MBExecutive Editor Michael Roy speaks with Sara K. Blaine, Ph.D., and Rajita Sinha, Ph.D., about their article on the use of brain imaging in the evaluation of drinking outcomes during early outpatient treatment for alcohol use disorder. Dr. Sara Blaine is an assistant professor in the Department of Psychological Sciences at Auburn University. She recently completed postdoctoral work at Yale University. Her work has looked at how genes and aspects of the brain affect the development of alcoh...
October 2020: Burnout and Depression Among Psychiatrists
October 01, 2020 11:30 - 33 minutes - 32.5 MBExecutive Editor Michael Roy speaks with Constance Guille, M.D., and Richard F. Summers, M.D., about their article on the prevalence of burnout and depressive symptoms among North American psychiatrists, demographic and practice characteristics associated with risk for these symptoms, and the correlation between burnout and depression. A related commentary on burnout by Dr. Summers also is discussed. Dr. Guille is a professor in the Departments of Psychiatry and Behavioral Sciences and of ...
September 2020: Callous-Unemotional Traits and Gun Violence
September 01, 2020 11:30 - 24 minutes - 23.8 MBExecutive Editor Michael Roy speaks with Emily Robertson, M.A., and Paul Frick, Ph.D., about their article on the role that callous-unemotional traits have in the risk for gun carrying and gun use during a crime. Ms. Emily Robertson is a clinical psychology doctoral student in the Developmental Psychopathology Lab at Louisiana State University. This fall, she begins a predoctoral internship at the Mailman Center for Child Development in the Miller School of Medicine at the University of Mi...
August 2020: Hormonal Treatments for Major Depressive Disorder
August 01, 2020 11:30 - 45 minutes - 42.8 MBExecutive Editor Michael Roy speaks with Jennifer Dwyer, M.D., Ph.D., and Awais Aftab, M.D., about the physiology of three major endocrine systems and about the evidence for hormone-based interventions in the treatment of major depressive disorder. Dr. Dwyer is an assistant professor at Yale University, where she is affiliated with the Child Study Center and the Department of Radiology and Biomedical Imaging. Dr. Aftab is a clinical assistant professor in the Department of Psychiatry at Ca...
July 2020: Association Between the Use of Cannabis and Physical Violence in Youths
July 01, 2020 11:30 - 27 minutes - 27.3 MBExecutive Editor Michael Roy speaks with Stéphane Potvin, Ph.D., and Alexandre Dumais, M.D., Ph.D., about their meta-analysis investigating the association between cannabis use and violence, and, more specifically, the perpetration of any type of physical violence by adolescents and young adults. How prevalent is the use of cannabis among young people? [2:23] What are some of the adverse outcomes that are linked to the use of cannabis, and are these outcomes linked to other difficulties o...
June 2020: Sleep Patterns in Children With Autism Spectrum Disorder
June 01, 2020 11:30 - 21 minutes - 21.2 MBExecutive Editor Michael Roy speaks with Katherine MacDuffie, Ph.D., and Annette Estes, Ph.D., about their longitudinal neuroimaging study examining associations between sleep difficulties and developmental trajectories among infants who go on to develop autism spectrum disorder. Why is sleep so important during early life? [2:16] How can sleep affect a child's behavioral and mental development, as well as overall functioning? [3:34] Why the authors conducted this research [4:47] Area...
May 2020: Psychedelics and Psychedelic-Assisted Psychotherapy
May 01, 2020 11:30 - 28 minutes - 26.3 MBExecutive Editor Michael Roy speaks with Collin Reiff, M.D., and William McDonald, M.D., about their evidence-based summary of the literature on the clinical application of psychedelic drugs in psychiatric disorders. How hallucinogens were first used, and some of the key individuals involved in the development of these drugs for medical use [2:23] What led to the worry about use of these compounds in the 1960s, and what actions did U.S. policymakers take at the time? [5:35] How have opi...
April 2020: Incidence of Psychotic Experiences From Childhood to Adulthood, and Prediction of Psychotic Disorder
April 01, 2020 11:30 - 16 minutes - 17.3 MBExecutive Editor Michael Roy speaks with Sarah A. Sullivan, Ph.D., and Stanley Zammit, Ph.D., about their research on the incidence, course, and outcome of psychotic experiences from childhood through early adulthood in the general population, and the prediction of psychotic disorder. How common are psychotic experiences in the general population, and what burdens do they place on public health systems? [2:19] What kinds of services are available to identify and treat individuals who have...
March 2020: Efficacy of Deep Brain Stimulation for Obsessive-Compulsive Disorder
March 01, 2020 12:30 - 19 minutes - 20.2 MBExecutive Editor Michael Roy speaks with Damiaan Denys, M.D., Ph.D., and Ilse Graat, M.D., about their research on the tolerability and effectiveness of deep brain stimulation (DBS) for patients with refractory obsessive-compulsive disorder (OCD). What characterizes OCD, and how widespread is it? [2:35] What treatment with DBS involves [4:07] Outline of study methods [6:25] Why the part of the brain studied is relevant for DBS, and description of the scales used to measure how well th...
February 2020: Adverse Outcomes Following Buprenorphine Discontinuation
February 01, 2020 12:30 - 26 minutes - 28.8 MBExecutive Editor Michael Roy speaks with Arthur Robin Williams, M.D., M.B.E., and Mark Olfson, M.D., M.P.H., about their research on adverse health outcomes following discontinuation of buprenorphine among Medicaid beneficiaries who were retained for variable periods beyond 6 months. How buprenorphine helps patients, and factors affecting the use of this medication [2:50] Are there any quality measures for buprenorphine or for the treatment of opioid use disorder more generally? [7:48] ...
January 2020: Maternal Bacterial Infection and Offspring Psychosis Risk
January 01, 2020 12:30 - 23 minutes - 26.5 MBExecutive Editor Michael Roy speaks with Younga H. Lee, Ph.D., and Stephen L. Buka, Sc.D., about their research on the association between maternal bacterial infection during pregnancy and risk for psychotic disorders in offspring. The New England Family Study [2:50] Study design [7:21] How information about exposure to bacterial infection was collected, and how offspring who developed mental health problems were evaluated [8:07] Main findings with regard to the connection between exp...
December 2019: Dimensions of Psychopathology and Brain Structure
December 01, 2019 12:30 - 17 minutes - 17.9 MBExecutive Editor Michael Roy speaks with Antonia Kaczkurkin, Ph.D., and Theodore Satterthwaite, M.D., about their research on how different measures of brain structure (cortical thickness and volume) in youths are associated with various dimensions of psychopathology. What this study aimed to achieve [3:19] Dimensions of psychopathology identified in the study [6:33] Description of a novel method to identify structural brain networks [8:17] Main findings of the research [9:53] Wheth...